棋牌游戏平台-棋牌游戏赚钱qq群

出生年

1988.10

民族

漢

職稱

副教授

學科專業

生物醫學工程

研究方向

神經生物學

電子郵箱

jiawei-min@hotmail.com

簡歷

博士，副教授，碩士生導師。2016年6月博士畢業于武漢大學基礎醫學院。畢業后先后在美國Sanford School of Medicine, University of South Dakota和美國University of Texas Health Science Center at Houston任博士后研究員，2019年10月回國加盟中南民族大學生物醫學工程學院。現為美國心臟協會(AHA)會員，中國神經科學學會會員，湖北省生理學會會員，武漢市生理學會理事。并受邀成為SCI期刊《Frontiers in Pharmacology》和《Journal of Integrative Neuroscience》的客座編輯且多次擔任SCI雜志Stroke; Iscience; Brain Research Bulletin; Clinical Epidemiology; Neuroreport; Journal of Molecular Neuroscience等審稿人。同時，擔任教育部學位與研究生教育發展中心評審專家。近年來發表SCI論文20多篇，其中第一作者或通訊作者14篇，總引用超過1000余次，其中ESI高引1篇。目前主持國家自然科學基金項目1項、湖北省自然科學基金項目2項、中央高校基本科研業務費專項資金項目1項、中南民族大學引進人才項目1項，并參與多個國家級和省級項目。本課題組主要研究領域為新生兒缺氧缺血性腦病和成年人缺血性腦卒中的發病機制及靶向干預的研究。專注于①探究鈣/鈣調蛋白依賴性蛋白激酶激酶β（CaMKKβ）在上述兩種疾病中的神經保護作用及其機制；②利用網絡藥理學、分子對接、SPR、代謝組學和轉錄組學等技術，篩選具有改善上述兩種疾病的小分子化合物或中藥單體。

近年代表性研究成果（論文、專著、獲獎、專利等）

第一作者或者通訊作者文章（#為共同一作；*為通訊作者）：

1. Liu XJ, Zheng D, Chen L, Chen S*, Min JW*. Nuclear Factor Erythroid 2-Related Factor 2 as a Potential Therapeutic Target in Neonatal Hypoxic-Ischemic Encephalopathy. J Integr Neurosci. 2024, 23(5), 103.

2. Chen L, Chen S, Yang XF, Min JW*. Antioxidants attenuate mitochondrial oxidative damage through the Nrf2 pathway: A promising therapeutic strategy for stroke. J Neurosci Res 2023. 101(8), 1275–1288.

3. Li Y, Chen L, Zheng D, Liu JX, Liu C, Qi SH, Hu PC, Yang XF and Min JW*. Echinocystic acid alleviated hypoxic-ischemic brain damage in neonatal mice by activating the PI3K/Akt/ Nrf2 signaling pathway. Front. Pharmacol. (2023)14:1103265.

4. Li Y, Zhang JJ, Chen RJ, Chen L, Chen S, Yang XF, Min JW*. Genistein Mitigates Oxidative Stress and Inflammation by Regulating Nrf2/HO-1 and NF-κB Signaling Pathways in Hypoxic-Ischemic Brain Damage in Neonatal Mice. Ann Transl Med. 2022 Jan;10(2):32.

5. Zhang JJ, Li Y, Chen S, Yang XF, Min JW*. Biphalin, a dimeric opioid peptide, reduces neonatal hypoxia-ischemia brain injury in mice by the activation of PI3K/Akt signaling pathway. J Chem Neuroanat. 2021 Sep;115:101967.

6. Liu Y#, Min JW#, Feng S, Subedi K, Qiao F, Mammenga E, Callegari E, Wang H.Therapeutic Role of a Cysteine Precursor, OTC, in Ischemic Stroke Is Mediated by Improved Proteostasis in Mice. Transl Stroke Res. 2020 Feb;11(1):147-160.

7. Min JW, Bu F, Qi L, Munshi Y, Kim GS, Marrelli SP, McCullough LD, Li J. Inhibition of Calcium/Calmodulin-Dependent Protein Kinase Kinase β Is Detrimental in Hypoxia?Ischemia Neonatal Brain Injury. Int J Mol Sci. 2019 Apr 26;20(9):2063.

8. Min JW, Liu Y, Wang D, Qiao F, Wang H. The non-peptidic δ-opioid receptor agonist Tan-67 mediates neuroprotection post-ischemically and is associated with altered amyloid precursor protein expression, maturation and processing in mice. J Neurochem. 2018 Feb;144(3):336-347.

9. Min JW, Kong WL, Han S, Bsoul N, Liu WH, He XH, Sanchez RM, Peng BW. Vitexin protects against hypoxic-ischemic injury via inhibiting Ca2+/Calmodulin-dependent protein kinase II and apoptosis signaling in the neonatal mouse brain. Oncotarget. 2017 Apr 11;8(15):25513-25524.

10. Min JW, Lü L, Freeling JL, Martin DS, Wang H. USP14 inhibitor attenuates cerebral ischemia/reperfusion-induced neuronal injury in mice. J Neurochem. 2017 Mar;140(5):826-833.

11. He M#, Min JW#, Kong WL, He XH, Li JX, Peng BW. A review on the pharmacological effects of vitexin and isovitexin. Fitoterapia. 2016 Dec;115:74-85. （ESI高引）

12. Min JW, Hu JJ, He M, Sanchez RM, Huang WX, Liu YQ, Bsoul NB, Han S, Yin J, Liu WH, He XH, Peng BW. Vitexin reduces hypoxia-ischemia neonatal brain injury by the inhibition of HIF-1alpha in a rat pup model. Neuropharmacology. 2015 Dec;99:38-50.

13. Min JW, Peng BW, He X, Zhang Y, Li JX. Gender difference in epileptogenic effects of 2-BFI and BU224 in mice. Eur J Pharmacol. 2013 Oct 15;718(1-3):81-6.

14. Min JW, Liu WH, He XH, Peng BW. Different types of toxins targeting TRPV1 in pain. Toxicon. 2013 Sep